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Profile Comparer: a program for scoring and aligning profile hidden Markov models

Martin Madera, Profile Comparer: a program for scoring and aligning profile hidden Markov models. Bioinformatics, 24(22). ISSN 1367-4803, pp. 2630–2631. October 2008. PDF, 99 Kbytes. External information

Abstract

Profile Comparer (PRC) is a stand-alone program for scoring and aligning profile hidden Markov models (HMMs) of protein families. PRC can read models produced by SAM and HMMER, two popular profile HMM packages, as well as PSI-BLAST checkpoint files. This application note provides a brief description of the profile–profile algorithm used by PRC.

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